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Updated: Aug 30, 2025

High-throughput Screening of Chemical Compounds to Elucidate Their Effects on Bacterial Persistence
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亜致死性シトクロームcの放出により,薬剤耐性の持続細胞が生成される

Halime Kalkavan1, Mark J Chen1, Jeremy C Crawford1

  • 1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Cell
|September 2, 2022
PubMed
まとめ

薬剤耐性の持続細胞は 癌治療を回避する 亜致死性ミトコンドリア損傷とシトクロームcの放出により ストレス反応が引き起こされ,フェロプトーシスに脆弱な 持続細胞が生成されます.

キーワード:
ATF4 についてBcl-2ファミリーGPX4 についてHRI についてフェロプトーシス統合ストレス反応が持続する

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