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Updated: Aug 29, 2025

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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非リボソーム性ペプチド合成酵素のサイト固有の挿入のための再プログラム

Anna Camus1, Gisèle Truong1, Peer R E Mittl2

  • 1Laboratory of Organic Chemistry, ETH Zürich, 8093 Zurich, Switzerland.

Journal of the American Chemical Society
|September 7, 2022
PubMed
まとめ

研究者は,アミノ酸からヒドロキシ酸に基板特異性を切り替えるために,生物合成経路でゲートキーパー酵素を設計しました. これにより,医薬品用新しいペプチドおよびデプシペプチド類の効率的な生産が可能になります.

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