関連する実験動画

Updated: Aug 29, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

Published on: December 16, 2021

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新しい抗原を提示する細胞は,腸内微生物群にTreg依存の耐性を与えます

Blossom Akagbosu1, Zakieh Tayyebi2,3, Gayathri Shibu1,4

  • 1Immuno-Oncology, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, USA.

Nature
|September 7, 2022
PubMed
まとめ

研究者らは,RORγt+抗原を提示する細胞の新型であるThetis細胞を特定し,生命の初期に周辺の免疫耐性を確立するために決定的な役割を果たした. これらの細胞,特にTCIVサブセットは,腸内炎症を予防する T (Treg) 細胞の生成に不可欠です.

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