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Updated: Aug 29, 2025

Extracting Modified Microtubules from Mammalian Cells to Study Microtubule-Protein Complexes by Cryo-Electron Microscopy
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Extracting Modified Microtubules from Mammalian Cells to Study Microtubule-Protein Complexes by Cryo-Electron Microscopy

Published on: March 3, 2023

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マイクロチューブルのダイネイン-ダイナクチンの構造は,タンデムアダプター結合を示している

Sami Chaaban1, Andrew P Carter2

  • 1Division of Structural Studies, Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

Nature
|September 7, 2022
PubMed
まとめ

マイクロチューブルモーターである細胞質のダイネインは,ダイナクチンとアダプターによって活性化されます. この研究は,マイクロチューブルに結合したダイネイン-ダイナクチン-アダプター複合体の高解像度構造を明らかにし,それらの相互作用と運動行動を詳細に説明しています.

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