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Updated: Aug 29, 2025

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ヒトの減少葉酸媒介体SLC19A1によるメトレクサートの認識

Nicholas J Wright1, Justin G Fedor1, Han Zhang2

  • 1Department of Biochemistry, Duke University School of Medicine, Durham, NC, USA.

Nature
|September 7, 2022
PubMed
まとめ

ヒトの低葉酸キャリア (hRFC) は,必須の葉酸と化学療法薬を輸入しています. 新しい構造は hRFC がこれらの重要な分子を認識し 輸送する方法を明らかにし 薬の感受性に影響を与えます

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