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Updated: May 5, 2026

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5
10:05

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5

Published on: November 13, 2015

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TBX20は,ヒトの直接的な心臓再プログラム中に収縮性とミトコンドリア機能を改善する

Yawen Tang1, Sajesan Aryal2,3, Xiaoxiao Geng1

  • 1Department of Biomedical Engineering (Y.T., X.G., V.G.F., J.Z., Y.Z.), Heersink School of Medicine, School of Engineering, University of Alabama at Birmingham.

Circulation
|September 14, 2022
PubMed
まとめ

再プログラムカクテルに TBX20 を加えると 機能的な心筋細胞に 直接的な心臓の再プログラムが改善されます これは心臓の機能とミトコンドリアの呼吸を向上させ 心筋修復の有望な戦略を提供します

キーワード:
細胞を再プログラムするフィブロブラスト心臓筋細胞,心臓再生する転写因子

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