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Updated: Aug 28, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Published on: October 27, 2020

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暗黒のTGFβを介して加速器-ブレーキのメカニカルフィードバックをパターン化して,腸を回転させます

Bhargav D Sanketi1, Noam Zuela-Sopilniak2, Elizabeth Bundschuh1

  • 1Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

Science (New York, N.Y.)
|September 22, 2022
PubMed
まとめ

胚の腸の回転は,Pitx2発現を調節するために,Nodalではなく,新しいTGFβシグナル伝達経路に依存しています. このメカニズムは組織の硬さを調整し,対称性を破ることで適切な腸の発達を保証します.

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