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Updated: Aug 27, 2025

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
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編集者訂正: RORγt+細胞は腸内微生物に特有のTreg細胞の分化を指示する

Ranit Kedmi1, Tariq A Najar1, Kailin R Mesa1

  • 1Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.

Nature
|September 23, 2022
PubMed
まとめ

No abstract available in PubMed .

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Renewal of Intestinal Stem Cells

The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
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