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Updated: Aug 27, 2025

Restraint to Induce Stress in Mice and Rats
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ERのストレスは,ランダムな嗅覚受容体の選択を軸索のターゲティング精度に変換する

Hani J Shayya1, Jerome K Kahiapo2, Rachel Duffié3

  • 1Mortimer B. Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY 10027, USA; Medical Scientist Training Program, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

Cell
|September 27, 2022
PubMed
まとめ

展開されたタンパク質応答 (UPR) 経路,特にPERKシグナリングは,嗅覚神経の軸索標的を導く. このプロセスは嗅覚受容体のアイデンティティを 遺伝子発現と結び付け 嗅覚球の正確な配線を確保します

キーワード:
Ddit3 についてPERK についてアクソン誘導アクソンターゲティング細胞粘着細胞外バーコード嗅覚受容体ストキャスティックな遺伝子選択転写ネットワーク解き放たれたタンパク質反応

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