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Updated: Aug 27, 2025

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation

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メタボライトによる抗腫瘍免疫

James A Nathan1

  • 1Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), Department of Medicine, University of Cambridge, Cambridge, UK.

Science (New York, N.Y.)
|September 29, 2022
PubMed
まとめ

重要なエネルギー経路であるT細胞の糖分分解を阻害することで,腫瘍代謝物質は癌の免疫を乱します. この代謝干渉は,腫瘍細胞を排除する免疫システムの能力を低下させます.

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