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Updated: Aug 27, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

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ウイルスは,細菌の防御を克服するためにTIR gcADPRシグナル伝達を阻害する

Azita Leavitt1, Erez Yirmiya1, Gil Amitai1

  • 1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

Nature
|September 29, 2022
PubMed
まとめ

Tad1と呼ばれるファージタンパク質はスポンジとして作用し,Toll/インタールイキン-1受容体 (TIR) ドメインによって生成される免疫シグナル分子を隔離します. このメカニズムは 細菌と植物の免疫を抑制し 新しい病原体の防御戦略を明らかにします

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