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Updated: Aug 26, 2025

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy
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Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

Published on: June 27, 2018

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保存されたヒスティジン残留は,強化された非典型的に分割されたインテインにおけるエクステイン依存を誘発する

Giridhar Sekar1, Adam J Stevens2, Anahita Z Mostafavi2

  • 1Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.

Journal of the American Chemical Society
|October 4, 2022
PubMed
まとめ

研究者たちは,隣接するエクステン配列によって引き起こされる制限を克服するために,新しいタンパク質トランスプレイスング (PTS) システム,Cat*を設計しました. この強化されたシステムは,挑戦的なN-エクステン残留物との改善された活動を示し,PTSのアプリケーションを拡張します.

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