関連する実験動画

Updated: Aug 26, 2025

"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM
10:07

"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM

Published on: August 26, 2016

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ER表面のカルシウムトランジエントは,オートファゴソーム開始部位を指定するために,FIP200の液体-液体相分離を誘発する

Qiaoxia Zheng1, Yong Chen1, Di Chen1

  • 1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Cell
|October 5, 2022
PubMed
まとめ

多細胞生物における自食性の開始は,カルシウム (Ca2+) 変異体に依存する. EPG-4/ EI24によって調節されるこれらのトランジタは,ER膜のFIP200複合体の形成を誘発し,自己ファゴソームのバイオゲネシスを開始します.

キーワード:
ATG9 についてCa ((2+) 暫定的なEI24 についてER についてFIP200 についてオートファゴソーム形成液体-液体相分離リソソーム

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Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms13:40

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms

Published on: July 7, 2011

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Direct Imaging of ER Calcium with Targeted-Esterase Induced Dye Loading TED09:32

Direct Imaging of ER Calcium with Targeted-Esterase Induced Dye Loading TED

Published on: May 7, 2013

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Post-translational Translocation of Proteins to the RER01:27

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Targeting proteins to the ER
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In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
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Sec61 protein conducting channel
In eukaryotes, the translocon complex comprises a core heterotrimeric translocator channel called the Sec61 complex. This channel includes three transmembrane proteins, Sec61α, Sec61β, and Sec61γ, and is the largest subunit of the...
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