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Updated: Aug 26, 2025

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
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66,083 人のゲノムの核埋め込みミトコンドリア DNA 配列

Wei Wei1,2, Katherine R Schon1,2,3, Greg Elgar4

  • 1Department of Clinical Neuroscience, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

Nature
|October 5, 2022
PubMed
まとめ

ミトコンドリアDNA (mtDNA) は細胞核に継続的に転送され,核-ミトコンドリアセグメント (NUMT) が生成されます. これらのNUMTはmtDNAとは異なって進化し,新しい挿入が生殖系と癌で発生し,ダイナミックなヒトゲノムを形成します.

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