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Updated: Aug 26, 2025

Pancreatic Tissue Dissection to Isolate Viable Single Cells
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コラーゲノリシスに依存するDDR1シグナリングは,臓がんの結果を決定する

Hua Su1, Fei Yang2, Rao Fu2

  • 1Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.

Nature
|October 5, 2022
PubMed
まとめ

マトリックス・メタロプロテアゼで割れたI型コラーゲン (cCol I) は,DDR1シグナリングを活性化することによって臓がんの成長を促進し,無傷のI型コラーゲン (iCol I) はそれを抑制する. この経路は患者の生存に影響を与え 治療目標を提供します

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