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Updated: Aug 26, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions

Published on: August 2, 2018

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低酸素誘導因子1αによるγ-グロービン発現の活性化

Ruopeng Feng1, Thiyagaraj Mayuranathan1, Peng Huang2

  • 1Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.

Nature
|October 12, 2022
PubMed
まとめ

研究者は,VHL-HIF1α経路をターゲットにすることで,赤血球 (RBC) の胎児のヘモグロビン (HbF) 産生を促進する新しい方法を特定しました. この発見は,状細胞病や β-タラセミアなどの血液疾患の治療に 潜在的治療戦略を提供する.

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