関連する実験動画

Updated: Aug 25, 2025

Imaging G-protein Coupled Receptor GPCR-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum
09:40

Imaging G-protein Coupled Receptor GPCR-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum

Published on: September 20, 2011

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GPC3-Unc5受容体複合体の構造と細胞移動における役割

Onno Akkermans1, Céline Delloye-Bourgeois2, Claudia Peregrina3

  • 1Department of Biochemistry, University of Oxford, Oxford, UK.

Cell
|October 14, 2022
PubMed
まとめ

この研究は,グリピカン-3 (GPC3) に結合するアンコーディネート-5受容体D (Unc5D) の構造を明らかにし,その相互作用が神経細胞の移動と癌細胞の拡散をどのように導いているかを明らかにした.

キーワード:
GPC3 についてUNC5AUNC5BUNC5CUNC5DUnc5 についてセルガイド細胞の移動皮質の発達クリスタルグラフィーグリピカン-3ナノボディ神経芽細胞腫ストライプアッセイ構造生物学表面プラズモンの共鳴調整されていない-5

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