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Updated: Aug 25, 2025

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
08:46

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

8.8K

プリバイオティクヌクレオシド合成における補助物質および中間物質としてのアゾール

Dougal J Ritson1, Mikolaj W Poplawski2, Andrew D Bond2

  • 1MRC - Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, U.K.

Journal of the American Chemical Society
|October 17, 2022
PubMed
まとめ

この研究は,4,5-ディシアノイミダゾールが,プレバイオティックヌクレオチド合成の重要なステップであるシアノアセチレンを捕獲する方法を示しています. この進歩と 2アミノチアゾールの新合成は 生命の起源に関する シアノスルフィドシナリオを裏付けています

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