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Updated: Aug 24, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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(-) - ペイソンノサイドAのカタリシス対応13段階の総合合成

Bo Xu1, Chang Liu1, Mingji Dai1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|October 24, 2022
PubMed
まとめ

研究者らは,強力な抗菌剤であるディテルペイン・グルコシドである (-) - ペイスノシドAの13段階の合成を達成しました. この合成は,新しい移行金属触媒を用いて,保護基なしで構築されたユニークな,高度に置換されたサイクロプロパンリングを特徴としています.

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