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Updated: Aug 22, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

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ニッケル (IV) アミノキノリン誘導C (sp2) -C (sp3) カップリングにおける中間物質

Michael W Milbauer1, Jeff W Kampf1, Melanie S Sanford1

  • 1Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|November 8, 2022
PubMed
まとめ

研究者は安定したニッケル (IV) 複合体を分離し,C-H機能化触媒における重要な中間物質である. ピコリネートリガンドは この反応性種の安定化に鍵となり 触媒化学を進歩させた.

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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
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