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Updated: Aug 22, 2025

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チオペプチド生物合成中の酵素によるピリジン芳香化

Andrew J Rice1,2, Jarrett M Pelton3, Nicholas J Kramer3

  • 1Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|November 9, 2022
PubMed
まとめ

研究者は,チアゾールを含むピリチド (チオペプチド) のピリジン形成のメカニズムを解明した. この複雑な生物合成経路における最終的な芳香化のステップを容易にする重要なチロシン残基が特定されました.

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