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Updated: Aug 20, 2025

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
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Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry

Published on: October 15, 2018

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タンパク質複合体のガス相展開は,形状イソマーを区別する

Stacey Nash1, Richard W Vachet1,2

  • 1Molecular and Cellular Biology Program, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.

Journal of the American Chemical Society
|November 22, 2022
PubMed
まとめ

衝突誘発の展開とイオン移動質量スペクトロメトリーは,微妙なタンパク質構成状態を区別することができます. この方法は,ベータ・ラクトグローブリンをモデルとして用いて,明確な展開経路を明らかにし,タンパク質複合体の解離に意味を持っています.

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