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Updated: Aug 20, 2025

Quantification of Monocyte Chemotactic Activity In Vivo and Characterization of Blood Monocyte Derived Macrophages
09:57

Quantification of Monocyte Chemotactic Activity In Vivo and Characterization of Blood Monocyte Derived Macrophages

Published on: August 12, 2019

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マクロファージ由来25-ヒドロキシコレステロールは,血管炎症,アテロゲネシス,および損傷の再構築を促進する

Alberto Canfrán-Duque1,2,3, Noemi Rotllan1,2,3, Xinbo Zhang1,2,3

  • 1Vascular Biology and Therapeutics Program (A.C.-D., N.R., X.Z., J.S., N.L.P., M.F.-F., J.W.F., W.C.S., G.T., C.F.-H., Y.S.).

Circulation
|November 23, 2022
PubMed
まとめ

マクロファージによって生成される25-ヒドロキシコレステロール (25-HC) は,炎症とプラークの不安定性を高め,動脈硬化を加速します. このコレステロール系は炎症性遺伝子発現とアポトーシスを促進し,心血管疾患の進行に寄与します.

キーワード:
動脈硬化症炎症マクロファージオキシステロール

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