関連する実験動画

Updated: Aug 19, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
11:53

Substrate Generation for Endonucleases of CRISPR/Cas Systems

Published on: September 8, 2012

27.4K

タイプVのCRISPR関連トランポゾン複合体の構成基盤

Michael Schmitz1, Irma Querques1, Seraina Oberli1

  • 1Department of Biochemistry, University of Zurich, Zurich 8057, Switzerland.

Cell
|November 26, 2022
PubMed
まとめ

この研究は,CRISPR- Casシステムにおけるリボソームタンパク質S15の予期せぬ役割を明らかにし,特にタイプV- K要素によるRNA誘導トランスポーゼーションを明らかにした. この発見はCRISPRに関連したトランスポゾンアセンブリの重要なメカニズムを明らかにし,プログラム可能なDNA挿入ツールの開発を支援しています.

キーワード:
CAST (キャスト)CRISPRについてCRISPR-CasシステムCRISPRに関連するトランポゾンカス12kS15 についてTniQ についてTnsB についてTnsC についてトランポゾン

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