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Updated: May 4, 2026

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
12:03

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy

Published on: September 5, 2016

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ヒト免疫不全ウイルスのトランス活性化タンパク質によるmRNA蓄積の調節

M A Muesing, D H Smith, D J Capon

    Cell
    |February 27, 1987
    PubMed
    まとめ

    ヒト免疫不全ウイルス (HIV) のタットタンパク質は,メッセンジャーRNA (mRNA) レベルを上昇させることで,ウイルスの遺伝子発現を大幅に高めます. このTatタンパク質は,HIVのロング・ターミナル・リピート (LTR) 内の特定のRNA構造と相互作用して,ウイルスの複製を促進します.

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