関連する実験動画

Updated: Aug 19, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
06:10

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

404

T細胞受容体を再プログラムするナノ-バイオハイブリッドDNAエンゲージャー

Pei-Qiang Ma1, Tian-Xian Liu1, Hua-Dong Li1

  • 1Lab of Biosystem and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Journal of the American Chemical Society
|November 29, 2022
PubMed
まとめ

この研究は,がん治療のための新しいナノ-バイオハイブリッドDNAエンガージャー再プログラムT細胞受容体 (EN-TCR) システムを導入しています. EN-TCRは遺伝子工学を避け,T細胞の反応を強化することで,特異性,有効性,安全性を向上させます.

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