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Updated: Aug 18, 2025

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構造的変異は,がんにおける文脈依存性腫瘍遺伝子の活性化を誘発する

Zhichao Xu1, Dong-Sung Lee2, Sahaana Chandran1

  • 1Gene Expression Laboratory; Salk Institute for Biological Studies, La Jolla, CA, USA.

Nature
|December 8, 2022
PubMed
まとめ

3Dゲノム組織を変化させる構造変異 (SV) は,がんにおいて一般的です. アクティビティ・バイ・コンタクト・モデルは,特定のSVによる腫瘍遺伝子の活性化を予測し,異なる遺伝子調節モードを明らかにします.

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