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Updated: Aug 10, 2026

10:53
Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
二次元の超音波組織特徴: 逆分散力,内心臓壁の運動,および正常な心筋筋,缺血性心筋,心筋梗塞の相関係
P J Fitzgerald1, M D McDaniel, E L Rolett
1Cardiology Section, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Hanover, NH.
Circulation
|October 1, 1987
まとめ
超音波の逆分散力と犬の心筋の相差は,イシュケミアと心臓発作の間,予測可能に変化します. これらの変化は,組織の変化と壁の動きを反映し,心筋損傷の評価に関する洞察を提供します.
科学分野:
- 心血管の超音波検査です.
- 心筋のイメージング
- バイオメディカルエンジニアリング
背景:
- 心筋活性を非侵襲的に評価することは,心臓病の診断と管理に不可欠です.
- 超音波エネルギー反射特性により,健康な心臓組織と,不血症の心臓組織と,心臓梗塞の心臓組織を潜在的に区別することができる.
研究 の 目的:
- 誘発性イシュケミアおよび心臓発作中に犬の心筋から反射された超音波エネルギー (反射力および相) の変化を調査する.
- これらの超音波のパラメータを心内膜の動きと左心室の圧力と相関させるため.
主な方法:
- コントロールされた冠動脈閉塞 (2〜5時間) または一時的な絞り込み/再注射を受けた開胸犬に2D超音波スキャナーを使用しました.
- 測定された循環逆分散力 (BSP) と心内壁運動 (EWM),BSP,左心室圧 (LVP) の相差.
主要な成果:
- 循環性BSPは,イシェミア中に著しく低下し,心臓発作中に部分的に回復しました.
- EWMとBSPの相差は,イシェミアと心臓発作の間に徐々に増加した.
- 再輸血は,BSPと相差の両方を正常化しました.
- 心臓発作から5時間後,発動不振は全相差に46%を,反転散射力は54%を寄与した.
結論:
- 超音波の逆分散力と相変化は,心筋不全や心臓発作の敏感な指標である.
- これらのパラメータ,特に壁の動きとの相関係が,正常な心筋梗塞,不血性心筋梗塞,心筋梗塞を区別するのに役立ちます.
- この発見は,心筋損傷と生存可能性の超音波ベースの評価の可能性を示唆しています.
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