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Updated: Aug 16, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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ラセミゼーション条件と非対称な結晶の成長の相互作用によるキラル増幅

Sjoerd W van Dongen1, Imane Ahlal1, Michel Leeman2

  • 1AMOLF, Science Park 104, 1098 XGAmsterdam, The Netherlands.

Journal of the American Chemical Society
|December 19, 2022
PubMed
まとめ

キラル結晶は,以前の考えに反して,エナティオメア純度を増幅することができます. クロピドグレルのような有価な化合物のエナティオメア過剰を予想外に増強する.

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