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Updated: Aug 16, 2025

Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyltroponeiron
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Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyltroponeiron

Published on: August 12, 2019

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酵素カルベンの移転によるサイクルアミンのエナチオセレクティブ・シングルおよびダブルα-C-H結合機能化

Xinkun Ren1, Bo M Couture1, Ningyu Liu1

  • 1Department of Chemistry, University of Rochester, Rochester, New York 14627, United States.

Journal of the American Chemical Society
|December 21, 2022
PubMed
まとめ

この研究は,循環性アミンの直接非対称なC-H機能化のための鉄ベースの生物触媒法を導入します. エンジニアリングされた酵素は高収量とステレオ選択性を達成し,複雑な分子の効率的な合成を可能にします.

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