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Updated: Aug 16, 2025

Nanomanipulation of Single RNA Molecules by Optical Tweezers
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Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

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単分子フィールド効果トランジスタを用いたRNA幹ループのコンフォーマショナル・フリーエネルギー・ランドスケープの特徴付け

Sukjin S Jang1, Sarah Dubnik1, Jason Hon1

  • 1Department of Chemistry, Columbia University, 3000 Broadway, New York, New York10027, United States.

Journal of the American Chemical Society
|December 22, 2022
PubMed
まとめ

シングル分子フィールド効果トランジスタ (smFET) は,1-200msの時間スケールでRNA幹ループの折り畳みを明らかにします. これは単純なRNA構造でさえも 頑丈なエネルギー環境を示し RNAの折り畳みダイナミクスの新しい洞察を提供します

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