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Updated: Aug 16, 2025

Application of High-speed Super-resolution SPEED Microscopy in Live Primary Cilium
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IFT-Aのポリメリゼーションのメカニズム

Shimi Meleppattu1, Haixia Zhou1, Jin Dai1

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.

Cell
|December 23, 2022
PubMed
まとめ

イントラフラゲラ輸送 (IFT) の組み立てには,IFT-Aの複雑な再配置が含まれており,IFT列に協力的なポリメリゼーションが可能です. このメカニズムはIFT-AをIFT-Bと膜と相互作用しながら様々な荷物を結合させるように位置づけている.

キーワード:
シリアクリオ・エムクリオ・エットフラゲラフラゲル内輸送脂質結合マイクロチューブル分子輸送ベシクル

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