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Updated: Aug 15, 2025

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea
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シリアは,左-右非対称性を指示するカルシウム媒介メカニカセンサとして機能する

Lydia Djenoune1, Mohammed Mahamdeh1, Thai V Truong2

  • 1Cardiovascular Research Center, Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.

Science (New York, N.Y.)
|January 5, 2023
PubMed
まとめ

左右のオーガナイザー (LRO) の不動性シリアは 機械的な力を感知し 細胞のレバーとして作用します この機械感覚は生体力学的な力をカルシウム信号に変換し,脊椎動物における左-右非対称性を確立するのに不可欠です.

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