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Updated: Aug 15, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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オーガノカタリティック・エナチオセレクティブ・セール [4 + 4] サイクル添加物

Vasco Corti1, Casper Larsen Barløse1, Niklas Lawaetz Østergaard1

  • 1Department of Chemistry, Aarhus University, Aarhus C DK-8000, Denmark.

Journal of the American Chemical Society
|January 5, 2023
PubMed
まとめ

この研究は,キラル8基カーボサイクルの構築のための最初の有機触媒非対称 [4 + 4] サイクロアディションを導入する. この新しい方法は,高いステレオ制御で貴重なサイクロオクタディエンの誘導体への効率的なアクセスを提供します.

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