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Updated: Aug 14, 2025

Identification of Kinase-substrate Pairs Using High Throughput Screening
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人間のセリン/スレオニンキノームの基板特異性のアトラス

Jared L Johnson1,2, Tomer M Yaron1,2,3,4,5, Emily M Huntsman1,2

  • 1Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.

Nature
|January 11, 2023
PubMed
まとめ

この研究は,ヒトのタンパク質セリン/スレオニン (Ser/Thr) キナーゼの基板特異性をプロファイルし,多様なキナーゼ-基板相互作用を明らかにし,ヒト細胞における多数のリン酸化イベントに責任を負うキナーゼの識別を可能にします.

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