関連する実験動画

Updated: Aug 14, 2025

Using a Knee Arthrometer to Evaluate Tissue-specific Contributions to Knee Flexion Contracture in the Rat
04:59

Using a Knee Arthrometer to Evaluate Tissue-specific Contributions to Knee Flexion Contracture in the Rat

Published on: November 9, 2018

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感覚神経細胞の過剰なメカニカル伝導は,関節収縮を引き起こす

Shang Ma1, Adrienne E Dubin1, Luis O Romero2,3

  • 1Howard Hughes Medical Institute, Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|January 12, 2023
PubMed
まとめ

PIEZO2における機能獲得変異は,遠端関節縮症5型 (DA5) を引き起こします. 感覚ニューロンの過度に活発なメカノセンセーションは筋骨格の発達を妨げますが,PIEZO2を標的とした治療は有望です.

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