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Updated: Aug 14, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
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TBK1を標的とし,がん免疫療法に対する耐性を克服する

Yi Sun1, Or-Yam Revach1, Seth Anderson2

  • 1Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Nature
|January 12, 2023
PubMed
まとめ

TANK結合キナーゼ1 (TBK1) を標的にすることで,がんの免疫療法に対する抵抗を克服します. TBK1を阻害することでPD-1阻害に対する反応が強化され,患者による腫瘍モデルにおいて有望であり,効果的ながん治療のための新しい戦略を提供している.

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