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Updated: Aug 12, 2025

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
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フリデル・クラフト用,触媒的に生成されたミールワインの塩型オキシオニウムイオン C ((sp2) -H メチル化とメタノール

Tao He1, Hendrik F T Klare1, Martin Oestreich1

  • 1Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin, Germany.

Journal of the American Chemical Society
|February 1, 2023
PubMed
まとめ

この研究では,メタノールを用いてアレンを直接C-Hメチル化する新しい触媒法が導入されています. このプロセスは,温和な条件下で効率的なフリーデル・クラフトスアルキル化のための超電性メチル化剤を使用します.

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