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Updated: Aug 11, 2025

Covalent Fragment Screening Using the Quantitative Irreversible Tethering Assay
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Covalent Fragment Screening Using the Quantitative Irreversible Tethering Assay

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セルファム酸アセタミドは,共振性リガンド誘導放出化学のための自己燃焼性電極である

Rambabu N Reddi1, Adi Rogel1, Ronen Gabizon1

  • 1Dept. of Chemical and Structural Biology, The Weizmann Institute of Science, Rehovot 7610001, Israel.

Journal of the American Chemical Society
|February 4, 2023
PubMed
まとめ

新しい硫酸エレクトロフィルは,in vivoの共性ターゲティングのために調整可能な反応性を提供します. これらの化合物は,薬剤開発における反応性クロロアセタミドの代替品として有望であり,キナーゼ阻害およびタンパク質ラベリングの研究での有効性が示されています.

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