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Updated: Aug 11, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
10:28

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Published on: September 20, 2018

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改変されたH2A-H2Bのリサイクルにより,クロマチンの状態の短期記憶が得られる

Valentin Flury1, Nazaret Reverón-Gómez1, Nicolas Alcaraz1

  • 1Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, 2200 Copenhagen, Denmark; Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark.

Cell
|February 7, 2023
PubMed
まとめ

親のヒストンH2A-H2Bの改変はDNA複製中に正確にリサイクルされ,表遺伝子遺伝を保証します. このプロセスはクロマチンの状態の回復を導き,ゲノム調節と細胞のアイデンティティを維持します.

キーワード:
DNA複製H2A についてH2A.ZH2B についてクロマチンヒストン PTM クロストークヒストンのリサイクルポリコンブ翻訳後の修正ユビキチネーション

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