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Updated: Aug 9, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Published on: April 4, 2018

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マルチアセンストリー ゲノム・ワイド アソシエーション 大動脈狭窄症の研究 百万退役軍人プログラムで複数の新しい位置を特定する

Aeron M Small1,2, Gina M Peloso3,4, Jason Linefsky5,6

  • 1Cardiovascular Medicine Division, Department of Medicine, Brigham and Women's Hospital (A.M.S., C.J.O.), Harvard Medical School, Boston, MA.

Circulation
|February 21, 2023
PubMed
まとめ

ゲノム全体の関連研究では,一般的な心臓病である動脈狭窄症 (CAS) の6つの新しいゲノム領域が特定されました. 発見は,CASの発達における脂質代謝,炎症,肥満,および心血管疾患との遺伝的関連を強調しています.

キーワード:
大動脈弁の狭窄全ゲノム関連研究ゲノム学脂質タンパク質 (a)

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