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Updated: Aug 8, 2025

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システム性狼症に対するバリシチニブ: ダブルブラインド,ランダム化,プラセボ対照,第3相試験 (SLE- BRAVE- II)

Michelle Petri1, Ian N Bruce2, Thomas Dörner3

  • 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Lancet (London, England)
|February 27, 2023
PubMed
まとめ

バリシチニブは,全身性狼症 (SLE) に対する52週間の第3相試験において有意な効果を示さなかった. Janusキナーゼ阻害剤の安全性プロファイルは,以前の発見と一致しており,SLE患者では新しい安全性シグナルが見つかりませんでした.

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