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Updated: Aug 8, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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自己組み立てカプセルにおけるオキシメスの選択的結合と同体化

Kuppusamy Kanagaraj1, Rui Wang1, Ming-Kai Zhao1

  • 1Center for Supramolecular Chemistry & Catalysis and Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China.

Journal of the American Chemical Society
|March 1, 2023
PubMed
まとめ

研究者らは,アルドキシムのZ同位体を選択的に結合して分離する新しいカプセルを開発しました. この超分子システムは,カプセル内のE-Zイソメリゼーションを容易にし,新しい分離とイソメリゼーション戦略を提供します.

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Overview
Epoxides result from alkene oxidation, which can be achieved by a) air, b) peroxy acids, c) hypochlorous acids, and d) halohydrin cyclization.
Epoxidation with Peroxy Acids
Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of...
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