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Updated: Aug 8, 2025

Retroviral Infection of Murine Embryonic Stem Cell Derived Embryoid Body Cells for Analysis of Hematopoietic Differentiation
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USB1は血液形成の発達を調節するmiRNAデデニラゼである

Ho-Chang Jeong1,2, Siddharth Shukla3,4, Wilson Chun Fok1,2

  • 1Division of Hematology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.

Science (New York, N.Y.)
|March 2, 2023
PubMed
まとめ

ニュートロペニア (PN) によるポイキロダーマでは,RNA外核酵素USB1の変異が血液不全を引き起こす. PAPD5/7を阻害すると,マイクロRNAのレベルを回復させ,新しいPN療法が示唆される.

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