関連する実験動画

Updated: May 7, 2026

Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

Published on: March 12, 2015

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マクロファージ・フーマレート・ヒドラゼは,mtRNA媒介によるインターフェロン生成を抑制する

Alexander Hooftman1, Christian G Peace2, Dylan G Ryan3,4,5

  • 1School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. ahooftma@tcd.ie.

Nature
|March 8, 2023
PubMed
まとめ

マクロファージの代謝再配線にはアスパルテート-アルギニノスッキナートシャントが含まれます. FH抑制は炎症反応を増加させ,マクロファージの機能におけるFHの保護的役割を強調する.

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Highly Efficient Transfection of Primary Macrophages with In Vitro Transcribed mRNA06:46

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