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Updated: Aug 7, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
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新抗原を標的としたCD8+ T細胞のPD-1阻害療法に対する反応

Cristina Puig-Saus1,2,3,4, Barbara Sennino5, Songming Peng5

  • 1Division of Hematology-Oncology, Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA. cpuigsaus@mednet.ucla.edu.

Nature
|March 8, 2023
PubMed
まとめ

メラノーマにおける有効な抗プログラム死亡受容体-1 (PD-1) 免疫療法は,特定の変異を標的とする多塩基CD8+T細胞と関連している. これらのネオアンチゲン特異性T細胞は,血と腫瘍で繰り返し検出されます.

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