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単核非ヘム鉄酵素によるアジリジン形成のメカニズム研究

Lide Cha1, Jared C Paris2, Brady Zanella1

  • 1Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.

Journal of the American Chemical Society
|March 13, 2023
PubMed
まとめ

研究者達は アジリジンという 自然界にある反応性化合物を 作り出す酵素を特定しました 計算方法と in vitro 実験を用いて,C−H 結合の割れ方によるアジリジン環形成の新しい鉄依存メカニズムを明らかにした.

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