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Updated: Aug 6, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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ヘリカルキラルオクソニウムイオンにおけるステレオジェニック酸素の制御

Owen Smith1, Mihai V Popescu1,2, Madeleine J Hindson1

  • 1Chemistry Research Laboratory, University of Oxford, Oxford, UK.

Nature
|March 16, 2023
PubMed
まとめ

研究者は安定したキラル型トリアリロキソニウムイオンを開発し,このような化合物の典型的な反応性を克服しました. この突破により 酸素は 構造的に安定した分子の中で 唯一のステレオゲンな中心として機能します

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