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Updated: Aug 6, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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単一結合核愛性および電子愛性パラメータ:1,3-二極サイクロアディションの効率的なオーダーリングシステム

Le Li1, Robert J Mayer2, Armin R Ofial1

  • 1Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, Germany.

Journal of the American Chemical Society
|March 23, 2023
PubMed
まとめ

この研究は,1,3-二極サイクロアディションの反応速度を正確に予測するための新しい線形自由エネルギー関係を導入し,ディアゾアルカンの反応性を理解するためのフロンティア分子軌道理論のより正確な代替案を提供します.

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