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Updated: Aug 5, 2025

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
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Published on: June 30, 2016

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GSDMBの毛穴形成活動を制御する構造的メカニズム

Xiu Zhong1,2, Huan Zeng2,3,4, Zhiwei Zhou2,5

  • 1Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing, PR China.

Nature
|March 29, 2023
PubMed
まとめ

病原菌IpaH7.8はガスダーミンB (GSDMB) とガスダーミンD (GSDMD) のタンパク質を標的とする. GSDMB エクソン6のスプライシングは,癌細胞の反応に不可欠な,毛穴形成活動と熱死機能を決定する.

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